RAB11A and infection: Our studies in Rab11a KO A549 cells showed a similar 10-fold decrease in viral titers during high MOI infections at 24hpi (H5N1 MOI = 1; H3N2 MOI = 5; Fig 3F), suggesting that IAV genome assembly and cytoplasmic trafficking can occur in the complete absence of Rab11a, albeit less efficiently.