All of the risk calculators included type of hematuria, age, smoking status, and sex as variables.11,22,25,44 Cytologic evaluation was incorporated into 2 nomograms, and the nuclear matrix protein 22 (NMP22) urinary marker was included in 1 nomogram.22,26 The hematuria risk score calculator indicated the greatest AUC of 0.835 (95% CI, 0.789-0.880).45 In comparison, the hematuria risk index calculator had an AUC of 0.809 to 0.833 (95% CIs not reported) and, in 3 cohorts, indicated a discrimination for UTC prevalence of 0.3% to 0.5% in low-risk groups and 10.8% to 11.0% in high-risk groups. Here, NUMA1 is linked to Hematuria.