CNP and hydrops fetalis: The BNP-stimulated cGMP levels did not reach statistical significance from that of CNP stimulation in Sham at the untargeted (P = 0.06), TnI (P = 0.09) and AKAP18δ (P = 0.5) biosensors, but were significantly lower than CNP in HF across all biosensors (P < 0.005) (Figure 7D-F).