By dual luciferase reporting test, we found that luciferase activity was significantly reduced in ccRCC cells stimulated with PDCD4-WT and miR-106b-5p, but there were no evident differences in ccRCC cells transfected PDCD4-MUT and miR-106b-5p, as shown in Figure 3(b). Here, PDCD4 is linked to nonpapillary renal cell carcinoma.