We have previously demonstrated the function of miR-210 as an oncogenic miRNA that mediates chemoresistance to GEM via the protein kinase B/mammalian target of rapamycin (AKT/mTOR) signaling pathway in multiple pancreatic cancer cell lines and in an in vivo animal model (Yang et al., 2019). The gene discussed is AKT1; the disease is familial pancreatic carcinoma.