Because SARS-CoV-2 binds to ACE2 and requires TMPRSS2 for activation and previous reports have shown that the liver is one of the organs that is affected by the virus, we surveyed the human liver (from tumor and adjacent normal regions of hepatocellular carcinoma patients) by single-cell RNA-seq (scRNA-seq) to identify which cell type co-express these two genes. This evidence concerns the gene ACE2 and hepatocellular carcinoma.