Because ENO1 has been identified as an oncogene in several cancers (Nakajima et al., 1986; Tu et al., 2010; Song et al., 2014; Fu et al., 2015; Liu et al., 2015; Principe et al., 2015; Zhu et al., 2015, 2018; Niccolai et al., 2016; Qian et al., 2017; Zhan et al., 2017), it could be a potential novel target for thyroid carcinoma. Here, ENO1 is linked to cancer.