It has previously been shown that expression levels of 11 HDAC members in primary neuroblastomas are correlated with NB prognosis and stage (Oehme et al., 2009; Figure 1B) and that HDAC2 functionally interacts with MYCN (Lodrini et al., 2013; Duffy et al., 2016). The gene discussed is HDAC9; the disease is neuroblastoma.