ATP1A1 and Intellectual disability: Schlingmann et al. (9) first described three patients harboring the de novo variations c.905T>C[p.Leu302Arg], c.907G>C[p.Gly303Arg], and c.2576T>G[p.Met859Arg] (NM_000701) in ATP1A1, involving renal hypomagnesemia, refractory epilepsy, and intellectual disability[HOMGSMR2, MIM618314] (Table 2, cases 3, 4, and 5).