Once T cells have infiltrated the tumor tissue, they encounter tumor cells with the radiation-induced expression of several surface molecules and receptors, such as MHC-I molecules (10), the TNF-R superfamily (11, 12) and ligands for the NKG2D receptor (13), leading to enhanced tumor cell killing by CD8+ T cells and NK cells. The gene discussed is TNFRSF1A; the disease is neoplasm.