In that work, DANCR functioned similarly to SNHG2, downregulating TIMP metallopepitidase inhibitor 2/3 (TIMP2/3) by activating the binding of enhancer of zeste homolog 2 (EZH2) to the promoter of TIMP2/3, which accelerated PCa metastasis. Here, EZH2 is linked to posterior cortical atrophy.