BIRC5 and central nervous system cancer: Furthermore, the expression levels of Bcl-2 and Survivin in glioma cells were significantly decreased after their transfection with miR-193a-3p mimics, whereas no changes were seen in the level of Bad or Bax, indicating a functional interaction between miR-193a-3p and the classic cellular intrinsic apoptosis pathway both in vitro and in vivo.