The risk score of each ccRCC patient was calculated as follows:(2)Risk score=0.0632×Exp ADAM8 reads+−0.0989×Exp CGN reads+0.1336×Exp EIF4EBP1 reads+0.1039×Exp FOXM1 reads+−0.0263×Exp G6PC reads+0.0258×Exp HAMP reads+0.1703×Exp HTR2C reads+0.0460×Exp ITIH4 reads+0.1244×Exp LTB4R reads+0.0618×Exp MMP3 reads+−0.0531×Exp PLG reads+0.0259×Exp PRKCG reads+0.0332×Exp SAA1 reads+−0.0657×Exp VWF reads. The gene discussed is MMP3; the disease is nonpapillary renal cell carcinoma.