Importantly, the role of the CD8-CXCR3-CXCL9/10-IFNγ axis in the pathogenesis of nonsegmental vitiligo is becoming increasingly evident [10, 11]; however, targeting this pathway may lead to long-term adverse effects, such as skin cancer, as it plays a vital role in maintaining the cutaneous immunity [12]. Here, IFNG is linked to vitiligo.