So far, mainly in silico studies have been performed to analyze the influence of variants in the gene TMPRSS2 with regard to COVID-19 (Asselta et al., 2020; Barash et al., 2020; Fujikura and Uesaka, 2020; Ghafouri-Fard et al., 2020; Hou et al., 2020; Paniri et al., 2020; Russo et al., 2020; Senapati et al., 2020; Singh et al., 2020; Smatti et al., 2020; Vargas-Alarcón et al., 2020; Zarubin et al., 2020). This evidence concerns the gene TMPRSS2 and COVID-19.