CD2 expression was significantly positively correlated with TMB (p < 0.001, ρSpearman= 0.14) (Figure 6E), Regarding the analysis of clinicopathological characteristics, CD2 expression was associated with tumor size to some extent (Figure 6G), but not with overall TNM stage (Figure 6F), lymph node status (Figure 6H), or distant metastasis (Figure 6I). The gene discussed is CD2; the disease is neoplasm.