MYCN and neuroblastoma: As shown in Figures S1A, B, the EUH subset includes (i) MYC-driven neuroblastoma expressing high MYC and/or MYCN protein (8), (ii) Neuroblastoma with TERT overexpression due to genomic rearrangements (9–11), and (iii) Neuroblastoma of the ALT group due to ATRX loss (12, 13).