CTLA4 and combined immunodeficiency: Among AIC-PID patients, the PID diagnoses included partial DiGeorge syndrome (pDGS) (n=7), genetically uncharacterized CVID/CID (n=6), genetically defined CID as follows: CHH-RMRP (cartilage-hair hypoplasia secondary to defect in the RNA component of mitochondrial RNA processing endoribonuclease) (n=1), CTLA-4 (cytotoxic T-lymphocyte-associated protein 4 haploinsufficiency (n=1), IKAROS (IKZF1 gene defect) (n=1), and Kabuki syndrome (KM2TD gene defect) (n=1) (Table 1).