These data highlight that the absence of the IP impairs STAT3 signaling via dysregulated phosphorylation (Figure 8C and Supplementary Figures 5A, B), correlating with the observed reduced myeloid cell survival (Figures 8A, B) and altered T cell differentiation (Figures 7F, F’) in infected TKO mice in the chronic stage of infection. This evidence concerns the gene STAT3 and infection.