To determine the relative expression of the three IP catalytic-subunits LMP2 (Psmb9), LMP7 (Psmb8) and MECL-1 (Psmb10) during the acute and chronic neuroinflammatory stage of infection, mRNA and protein was isolated from brain homogenates of T. gondii infected wild type (WT) mice at day 28 post-infection (p.i.). The gene discussed is PSMB10; the disease is infection.