NLRP3 and stroke disorder: In the ischemic lesion of mice at day 3 after stroke (peak of inflammasome activation), over half of the NLRP3+ (DC: 24.55 ± 3.45%; Microglia: 18.43 ± 4.25%; Macrophage: 56.23 ± 13.33%, P < 0.001) or IL-1β+ (DC: 23.85 ± 1.92%; Microglia: 17.03 ± 1.65%; Macrophage: 59.35 ± 5.83%, P < 0.001) cells were macrophages (Figure 4A).