TNF and autoimmune myocarditis: Apigenin treatment ameliorated experimental autoimmune myocarditis in BALB/c mice by modulating TH1/TH2 balance through downregulation of TH1 cytokines (TNF-α, IL-2, and interferon γ) and up-regulation of TH2 cytokines (IL-4, IL-10) (Zhang et al., 2016).