A dose response was demonstrated in all three cell types shown in human nasal cells (Figure 1A) and immortalized CF1-16 and CF bronchial cells (Figure 2A) with a maximal serum concentration of 25% (Figures 1A, 2A), and a maximum IL-8 secretion of 22.30 ng/mL in the CF bronchial cells. This evidence concerns the gene CXCL8 and cystic fibrosis.