TGFB1 and Thrombocytopenia: Astilbin (119), as one of the active components of S. glabra, was reported to play an anti-thrombocytopenic role in rat bone marrow megakaryocytes by up-regulating transforming growth factor beta (TGF-β1) content and down-regulating thermoplastic polyolefin (TPO) content, which may be the effective component against thrombocytopenia (Tang et al., 2014).