A large number of previous studies have found that USP7 exhibits a high expression signature in a variety of malignant tumors, including myeloma (Chauhan et al., 2012), prostate (Qi et al., 2020), hepatocellular (Cai et al., 2015), ovarian cancer (Ma and Yu, 2016) and glioma (Cheng et al., 2013). The gene discussed is USP7; the disease is plasma cell myeloma.