Moreover, EBN restores the immune system in the context of infection by influencing viruses through regulation of pro-inflammatory cytokines, such as IL-6 and TNF-α, and cytokines with regulatory properties, such as IL-10 and CCL2, which are also involved in the progression of UC (Haghani et al., 2016; Lee et al., 2018). This evidence concerns the gene IL6 and infection.