There have also been reports of association between TDP-43 and DPR pathologies: dendritic-like aggregates of poly-GR co-localized almost completely with phosphorylated TDP-43 in C9orf72-ALS motor cortex but formed only a small proportion of these TDP-43 aggregates in total (Saberi et al., 2018); similarly, a proportion of both inclusions of poly-GR and poly-GA have been found to colocalize with TDP-43 in C9orf72-FTD/ALS hippocampus (Cook et al., 2020). The gene discussed is C9orf72; the disease is amyotrophic lateral sclerosis.