MLD, which results from a deficiency of the lysosomal enzyme arylsulfatase A (ARSA), is a leukodystrophy which exhibits neurological damage with similar phenotypes to that of CD, such as ataxia and seizures, in addition to early infantile or juvenile death (Neufeld, 1991; Biffi et al., 2006). This evidence concerns the gene ARSA and leukodystrophy.