Although AURKA SNP rs758099 is located in intron area, they also found that it could have an impact on gastric cancer development.30 Interestingly, Dai el al. used meta-analysis to indicate that AURKA SNP rs2273535 increased the risk of breast cancer especially among Asians, whereas, rs1047972 SNP reduced the risk of breast cancer in Caucasians 43. The gene discussed is AURKA; the disease is breast cancer.