When compared to the placebo group, L-GSH supplementation was able to significantly increase levels of IFN-γ (Figure 3A, B), TNF-α (Figure 3C, D), and IL-2 (Figure 3 E, F) levels found within supernatants of in vitro granulomas treated with everolimus in T2DM subjects. This evidence concerns the gene TNF and type 2 diabetes mellitus.