In accordance, former analysis in a large series of T1D patients tested for several organ-specific autoantibodies revealed an association between rs11755527 and serum antibodies to tyrosine phosphatase IA-2, to thyroid peroxidase, and a borderline relationship with circulating antibodies to the major adrenocortical antigen, 21-hydroxylase [54]. Here, TPO is linked to type 1 diabetes mellitus.