TP53INP1 has been reported to interact with PTEN-induced putative kinase 1 (PINK1) and with Parkin8, two proteins involved in multiple pathways essential for the maintenance of cell homeostasis under stressful conditions, including mitophagy, whose genes are associated with autosomal recessive forms of Parkinson’s disease (PD)9. This evidence concerns the gene TP53INP1 and Parkinson disease.