TRIM25 and colorectal carcinoma: In the paired samples, 66.0% (33/50) of the CRC tissues had a higher TRIM25 IHC score and 24.0% (12/50) of the CRC tissues had a lower TRIM25 IHC score than the adjacent normal tissues, and the remaining 10.0% (5/50) of the CRC tissues and adjacent normal tissues had the equal TRIM25 IHC score (Fig. 1B, C).