Of interest is our finding of prominent desmoplasia associated with CK7-positive (especially mixed type) invasive cancers, as cancer desmoplasia and/or “mesenchymal” molecular subtype have been linked to worse prognosis in several digestive cancers, including gastric [36], pancreatic [37] and intestinal cancers [23, 25, 38–40]. The gene discussed is KRT7; the disease is intestinal cancer.