CD274 and central nervous system cancer: A detailed analysis of PD-L1 expression in glioma showed that 24% of all glioma showed TPS of ≥ 50%, 14% showed TPS of 25–50%, 10% showed TPS of 10–25%, 4% showed TPS of 5–10%, 10% showed TPS of 1–5% and 38% showed TPS of < 1% (Fig. 2c).