CD274 and central nervous system cancer: An analysis of loss of heterozygosity of 1p and 19q (LOH 1p/19q) showed higher PD-L1 expression in gliomas without LOH 1p/19q (mean amounts of 30%) compared with LOH 1p/19q aberrant gliomas (mean amounts of 11%, p > 0.05, Fig. 3c).