We quantified mRNA levels corresponding to interneuron marker genes (PV and SST), plasticity genes known to be altered by OTX2 levels (Gadd45b, Arc, Nr4a1), and inflammatory/oxidative stress pathway genes (Mtnd4 and Iba1), given that mood disorders can be related to oxidative stress response [38, 39]. The gene discussed is ARC; the disease is mood disorder.