TNF and cancer: The obtained outcomes after KEGG enrichment analysis indicated that the signaling pathways could be classified into three signaling pathway modules, i.e., cancer (pancreatic cancer), immunology (T cell receptor signaling pathway, B cell receptor signaling pathway, Toll-like receptor signaling pathway, and NF-kappa B signaling pathway), and inflammation process (TNF signaling pathway, and inflammatory mediator regulation of TRP channels (Fig. 3D).