TRIP12 and breast cancer: A similar correlation is observed in the GSE5327 breast cancer dataset, obtained through the PROGgeneV2 online database25, which shows that lung metastasis-free survival is lower (p value = 0.00337; HR = 0.21(95% confidence interval (CI): 0.07–0.60)) in tumors with low TRIP12 as compared to tumors with high TRIP12 levels (Fig. 1d).