On the other hand, while the expression level of ACE2 is low in the entire brain (Allen Brain Atlas: Human brain (https://human.bainmap.org/microarray/search)), its expression level is high in some parts of the brain, including the striatum (i.e., the locus of necrotizing encephalopathy associated with COVID-19 [39]) and the choroid plexus, which is relevant to the case report on the detection of SARS-CoV-2 in cerebrospinal fluid (CSF) [40]. This evidence concerns the gene ACE2 and COVID-19.