Wen-jie Wang et al. constructed a prognostic model of 16 IRGs and a ceRNA network to predict the prognosis of HCC [57]; Junyu Long et.al developed a HCC immune prognostic model related to TP53 [28]; and Dengchuan Wang et al. reported a four-gene signature prognostic model related to immune infiltration through coexpression analysis [57]. The gene discussed is TP53; the disease is hepatocellular carcinoma.