This was carried out to determine whether NFAT2 expression influences BLCA tumor growth in vivo. Comparison of the control and NFAT2 knockdown mouse tumour groups was evaluated: knockdown of NFAT2 caused a significant ~4-fold reduction in tumor weight (Figure 13L) and ~2-fold reduction in tumor volume (Figure 13M). The gene discussed is NFATC1; the disease is bladder transitional cell carcinoma.