TNNI3 and cardiovascular disorder: Finally, DEPICT prioritized several genes in the cTnI loci that were associated with heart development, structure and function, and with cardiovascular diseases: NRAP, which is located in the HABP2 locus, is involved in sarcomere assembly during cardiomyocyte development (48) and is associated with familial cardiomyopathies (49), and mutations in TRIM63 have been associated with left-ventricular dysfunction and hypertrophic cardiomyopathy (50).