Especially during the initial period after cancer cell inoculation, cyclosporine may have caused more potently immunosuppression in the animals that had been subjected to bonding, due to the concomitant anti-inflammatory action of oxytocin, a neurohormone with essential role in the establishment of social interactions and pair bonding (Lutgendorf et al., 2005; Fagundes et al., 2011; Fuligni et al., 2009; Yuan et al., 2016; Carter and Perkeybile, 2018). Here, OXT is linked to cancer.