We also found that genes ATF6, ATP6V0A1, EGFR, MYC, P4HB and SPNS1were up‐regulated in the high‐risk group, which are all harmful prognostic factors, while APOL1, TP53INP1 and ZC3H12A were up‐regulated in the low‐risk group and significantly correlated with better prognosis in BLCA (Figure 1G,H). The gene discussed is P4HB; the disease is bladder transitional cell carcinoma.