Strikingly we found that BLCA tumours with the ATGRS low‐risk profile were infiltrated with effector immune cells including CD8+ T cells and NK CD56bright cells, while tumours from the ATGRS high‐risk group were filled with immunosuppressive cells such as Treg and macrophages (Figure 7A, Supplementary Table 3, and Supplementary Figure 6). This evidence concerns the gene CD8A and bladder transitional cell carcinoma.