For practical reasons, our hope is that this meta‐analysis will not represent just another endpoint of investigations, instead of a start to clarify the association of other genetic defects in IL‐6 gene with the risk for T2DM, as well as to elucidate the underlying molecular mechanisms of circulating IL‐6 concentrations in the onset and progression of T2DM. The gene discussed is IL6; the disease is type 2 diabetes mellitus.