Moreover, in TCGA colorectal and gastric cancer and the FUSCC gastric cancer cohorts, 54.55%, 77.27%, and 63.64% of patients with MMR gene mutations were diagnosed with MSI-H, respectively, and 80.00%, 69.86%, and 53.33% of patients diagnosed with MSI-H had at least one mutation in MMR genes. Here, MRC1 is linked to gastric cancer.