In the East Asian population TT: 0.200, GG: 0.276,GT: 0.524 (http://www.ensembl.org/).The MDM2 SNP309polymorphism was also found to increase the risk of colorectalcancer (Qin et al., 2013), breast cancer (Cheng et al., 2012) andliver cancer (Tang et al., 2014). Here, MDM2 is linked to cancer.