AKT1, top up- (FKBP5, SORT1, VNN1, and CST7) and downregulated (PRR5L, SH2B3, SULF2, PLEKHO1, and PTPN6) genes in sepsis were validated using RT-PCR (as shown in Figure 7). The gene discussed is SH2B3; the disease is Sepsis.