However, children with IP had lower serum levels of IL-6 (28.29 vs. 63.97 pg/ml, P < 0.001), IL-10 (5.88 vs. 8.59 pg/ml, P < 0.001), IFN-γ (14.55 vs. 43.29 pg/ml, P < 0.001) relative to children with PC. The gene discussed is IL6; the disease is pachyonychia congenita.