Interestingly, the rate of distant metastasis was significantly different between the FAM83A|high and IDO1|high groups in all cohorts (TCGA-CRC: 29 vs. 15%, p = 0.007; GSE29621: 46 vs. 17%, p = 0.031; GSE39084: 44 vs. 16%, p = 0.028; GSE18105: 49 vs. 23%, p = 0.021; GSE21510: 47 vs. 25%, p = 0.026; GSE27854: 45 vs. 18%, p = 0.006; and GSE71222: 24 vs. 8%, p = 0.012) (Figures 8A–G). The gene discussed is IDO1; the disease is colorectal carcinoma.