MET and neoplasm: MET is a proto-oncogene located on chromosome 7q21-31 and encodes a hepatocyte growth factor (HGF) receptor and acts as a carcinogenic driver in tumors, resulting in extensive downstream effects on tumor growth, invasiveness, angiogenesis, epithelial-mesenchymal transition and metastasis (An et al., 2014; Gherardi et al., 2012; Kim et al., 2018).The relationship between TP53 and MET gene abnormalities (such as mutations and amplifications) and clinical pathology in gastric cancer tissues has been studied (Baniak et al., 2016; Fenoglio-Preiser et al., 2003; Peng et al., 2014).